Jesús Alfredo Guzmán Salazar, also known as “Alfredo,” is a Mexican organized-crime figure and one of the sons of former Sinaloa Cartel leader Joaquín “El Chapo” Guzmán. U.S. authorities identify him as a senior figure in the faction known as Los Chapitos, alongside his brothers Iván Archivaldo Guzmán Salazar and Ovidio Guzmán López.
According to the U.S. Department of Justice, the Chapitos allegedly assumed a leadership role within the Sinaloa Cartel after their father's imprisonment. Federal prosecutors have accused Jesús Alfredo and his brothers of directing a transnational organization involved in the production and distribution of illicit drugs destined for the United States.
The U.S. federal case against Jesús Alfredo includes allegations involving fentanyl, cocaine, heroin and methamphetamine. An indictment unsealed in 2023 charged him with continuing criminal enterprise and conspiracies involving fentanyl importation and distribution, as well as other federal offenses. The indictment alleges that the Chapitos' organization operated across Mexico and the United States.
U.S. prosecutors have specifically described Jesús Alfredo and Iván Archivaldo as part of the leadership of the Sinaloa Cartel's Chapitos faction. Federal authorities allege that the organization developed an extensive international operation and generated substantial proceeds from drug trafficking. These statements represent allegations contained in federal proceedings and should not be interpreted as judicial findings of guilt.
Jesús Alfredo remains at large outside U.S. custody, according to the Department of Justice. In 2025, federal prosecutors stated that arrest warrants had been issued for both Jesús Alfredo and Iván Archivaldo, while the U.S. government offered rewards of up to $10 million for information leading to their arrest and conviction.
His case is part of the broader U.S. campaign against the Sinaloa Cartel and its alleged leadership structure. The organization has been the subject of numerous federal investigations and prosecutions, particularly concerning the trafficking of fentanyl and other controlled substances into the United States.
Despite the serious allegations against him, Jesús Alfredo Guzmán Salazar has not been convicted in the U.S. cases described above. Under U.S. law, the charges contained in an indictment are allegations, and defendants are presumed innocent unless proven guilty beyond a reasonable doubt.
The continuing pursuit of Jesús Alfredo also illustrates the legal and international significance of the Chapitos faction, whose members have become major targets of U.S. federal law-enforcement investigations following the imprisonment of their father, El Chapo.
SOURCES
U.S. Department of Justice — Sinaloa Cartel Leadership Charges
U.S. Department of Justice — Joaquin Guzman Lopez Federal Case
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